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Table. 1.

Table. 1.

Comparisons of prevalence of incidental findings, pituitary abnormalities and pathologic magnetic resonance imaging findings in central precocious puberty groups

Group 1 (boys) Group 2 (girls ≤6 yr) Group 3 (girls >6 yr) Control P-value
Central precocious puberty
No. of patients 19 17 94 224
Age (yr) 8.53±1.93 5.2±1.3 7.54±0.56 6.95±0.84
Magnetic resonance imaging features
Category 1: normal 7 (36.8) 3 (17.6) 44 (46.8) -
Category 2: incidental findings
Pineal cyst 4 (21.1) 8 (47.1)* 23 (24.5)* 25 (11.2) <0.001
Arachnoid cyst 1 (5.3) 0 (0) 5 (5.3) 8 (3.6) 0.698
Choroid plexus cyst 1 (5.3) 0 (0) 0 (0) 0 (0) 0.102
Subependymal heterotopia 0 (0) 0 (0) 1 (1.1) 0 (0) 0.367
Total 6 (31.6) 8 (47.1)* 28 (29.8)* 33 (14.7) <0.001
Category 3: pituitary abnormality
Hyperplasia 4 (21.1) 3 (17.6) 25 (26.6) - 0.762
Hypoplasia 3 (15.8) 7 (41.2) 13 (13.8) - 0.027
Rathket’s cleft cyst 1 (5.3) 1 (5.9) 6 (6.4) - >0.99
Pituitary adenoma 0 (0) 1 (1.1) 0 (0) - >0.99
Total 8 (42.1) 11 (64.7) 45 (47.9) - 0.353
Category 4: pathologic findings
Hypothalamic hamartoma 1 (5.3) 1 (5.9) 0 (0) - 0.075

Values are presented as mean±standard deviation or number (%).

*P<0.05 vs. control.

P<0.05 vs. >6 years.

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