pISSN 2234-3180eISSN 2234-2591
Table. 2.
Table. 2.
Etiologies and frequency of short stature
| Etiologies | Frequency |
|---|---|
| Normal variant | >60% |
| Familial short stature, constitutional delay of growth and puberty, idiopathic short stature | |
| Pathologic short stature | |
| Short stature related syndrome or chromosomal abnormalities | 5% |
| Turner syndrome, Noonan syndrome, Prader-Willi syndrome, Russel-Silver syndrome | |
| Skeletal dysplasia | 2% |
| Achondroplasia, hypochondroplasia | |
| Small for gestational age | 2% |
| Chronic systemic diseases | 2% |
| Malnutrition, kidney disease, endocrine disease, inflammatory bowel disease, cardiac and pulmonary disease | |
| Disorders of growth hormone-insulin-like growth factor-I axis | 2% |
| Growth hormone deficiency, growth hormone insensitivity, insulin-like growth factor-I deficiency | |
| Psychosocial deprivation | <1% |
Modified from Polidori N et al.
Ewha Med J 2021;44:111~116 https://doi.org/10.12771/emj.2021.44.4.111
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